USDA SBIR PHASE II - UC DAVIS VALIDATED - READY FOR PARTNERSHIP

The World’s First Scalable Oral Health Platform for Aquaculture

PhycoVax delivers vaccines, immune stimulants, growth promoters, and nutraceuticals directly as feed using diatoms with natural silica protection. No injections. No cold chain. Revolutionary health delivered simply. Naturally.

THE PROBLEM

Aquaculture disease is a $10B crisis

Current vaccines require injection — impossible for shrimp, impractical for tilapia, and economically unviable for high - volume, low-margin species

THE PLATFORM

Engineered for Scale

From gene to challenge in 6-9 months. From lab to 100,000L with proven technology.

01 Reverse Vaccinology Pipeline

Computational epitope discovery across 4,500+ Salmonella proteins. Multi-serotype cross-protection via bioinformatic antigen selection and epitope stacking

02 Diatom Expression System

Nuclear transformation of marine diatoms (Thalaassiosira, Cyclotella, Phaeodactylum). FACS selection, inducible promoters, multi-antigen capability.

Nature’s Perfect Health Delivery Platform:

DIATOM

Phycovax engineers marine diatoms to deliver a complete spectrum of health solutions — vaccines, immune stimulants, growth factors, and nutraceuticals — all protected within natural silica frustules that survive processing and targeted delivery.

  • Surivives 85 degree celcius feed pelleting — integrates into existing manufacturing

  • Shelf-stable as dried powder — no cold chain required

  • Multi-antigen stacking — single diatom, multiple vaccines

  • Proven oral efficacy — mucosal & systemic immune response

THE DATA

Proven efficacy across species

Peer-reviewed publications and controlled challenge studies.

Shrimp ( EMS/WSSV )

75%

Survival vs. Control

ShrimpVet Vietnam + PhycoVax Ecuador

Tilapia ( Francisella )

80%

Culmulative Survival

US Davis — Published Research

Poultry ( Salmonella )

27

Multi-Epitope Construct

6 serotype cross - protection